Randomized controlled trials in children's heart surgery in the 21st century: a systematic review.

ABSTRACT:

Objectives

Randomized controlled trials are the gold standard for evaluating health care interventions, yet are uncommon in children's heart surgery. We conducted a systematic review of clinical trials in paediatric cardiac surgery to evaluate the scope and quality of the current international literature.

Methods

We searched MEDLINE, CENTRAL and LILACS, and manually screened retrieved references and systematic reviews to identify all randomized controlled trials reporting the effect of any intervention on the conduct or outcomes of heart surgery in children published in any language since January 2000; secondary publications and those reporting inseparable adult data were excluded. Two reviewers independently screened studies for eligibility and extracted data; the Cochrane

SUBMITTER: Drury NE 

PROVIDER: S-EPMC5848812 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature