Improved magnetic regulation of delivery profiles from ferrogels.

ABSTRACT: While providing the ability to magnetically enhance delivery rates, ferrogels have not been able to produce the various types of regulated delivery profiles likely needed to direct complex biological processes. For example, magnetically triggered release after prolonged periods of payload retention have not been demonstrated and little has been accomplished towards remotely controlling release rate through alterations in the magnetic signal. Also, strategies do not exist for magnetically coordinating multi-drug sequences. The purpose of this study was to develop these capabilities through improved ferrogel design and investigating how alterations in the magnetic signal impact release characteristics. Results show that delivery rate can be remotely regulated using the frequency of magnetic

SUBMITTER: Kennedy S 

PROVIDER: S-EPMC5849080 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature