Hyperendemic dengue transmission and identification of a locally evolved DENV-3 lineage, Papua New Guinea 2007-2010.

ABSTRACT:

Background

Dengue is endemic in the Western Pacific and Oceania and the region reports more than 200,000 cases annually. Outbreaks of dengue and severe dengue occur regularly and movement of virus throughout the region has been reported. Disease surveillance systems, however, in many areas are not fully established and dengue incidence is underreported. Dengue epidemiology is likely least understood in Papua New Guinea (PNG), where the prototype DENV-2 strain New Guinea C was first isolated by Sabin in 1944 but where routine surveillance is not undertaken and little incidence and prevalence data is available.

Methodology/principal findings

Serum samples from individuals with recent acute febrile illness or with non-febrile conditions collected between 2007-2010 were tested f

SUBMITTER: Luang-Suarkia D 

PROVIDER: S-EPMC5849365 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature