Volumetric-based image guidance is superior to marker-based alignments for stereotactic body radiotherapy of prostate cancer.

ABSTRACT:

Purposes

The aim of this study was to evaluate a dual marker-based and soft-tissue based image guidance for inter-fractional corrections in stereotactic body radiotherapy (SBRT) of prostate cancer.

Methods/materials

We reviewed 18 patients treated with SBRT for prostate cancer. An endorectal balloon was inserted at simulation and each treatment. Planning margins were 3 mm/0 mm posteriorly. Prior to each treatment, a dual image guidance protocol was applied to align three makers using stereoscopic x ray images and then to the soft tissue using kilo-voltage cone beam CT (kV-CBCT). After treatment, prostate (CTV), rectal wall, and bladder were delineated on each kV-CBCT, and delivered dose was recalculated. Dosimetric endpoints were analyzed, including V_{36.25 Gy} for

SUBMITTER: Li W 

PROVIDER: S-EPMC5849820 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature