Validation of a deformable MRI to CT registration algorithm employing same day planning MRI for surrogate analysis.

ABSTRACT:

Purpose

Validating deformable multimodality image registrations is challenging due to intrinsic differences in signal characteristics and their spatial intensity distributions. Evaluating multimodality registrations using these spatial intensity distributions is also complicated by the fact that these metrics are often employed in the registration optimization process. This work evaluates rigid and deformable image registrations of the prostate in between diagnostic-MRI and radiation treatment planning-CT by utilizing a planning-MRI after fiducial marker placement as a surrogate. The surrogate allows for the direct quantitative analysis that can be difficult in the multimodality domain.

Methods

For thirteen prostate patients, T2 images were acquired at two different time poi

SUBMITTER: Padgett KR 

PROVIDER: S-EPMC5849829 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature