Propionibacterium avidum: A Virulent Pathogen Causing Hip Periprosthetic Joint Infection.

ABSTRACT:

Background

Propionibacteria are important members of the human skin microbiota, but are also opportunistic pathogens associated with periprosthetic joint infection (PJI). While the role of Propionibacterium acnes in PJI has been widely described, insight into the capacity of Propionibacterium avidum to cause PJI is limited.

Methods

An unusual cluster of 4 hip PJIs caused by P. avidum in one orthopedic center in 2015 prompted us to retrospectively identify and analyze clinical data related to previous P. avidum PJI cases (1997-2015). We also characterized the hemolytic and biofilm-producing capacity of our 4 clinical P. avidum strains isolated in 2015, and investigated their phylogenetic relationships by whole-genome sequencing.

Results

We retrospectively identified 13

SUBMITTER: Achermann Y 

PROVIDER: S-EPMC5850018 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature