Ovarian hormones and obesity.

ABSTRACT:

Background

Obesity is caused by an imbalance between energy intake, i.e. eating and energy expenditure (EE). Severe obesity is more prevalent in women than men worldwide, and obesity pathophysiology and the resultant obesity-related disease risks differ in women and men. The underlying mechanisms are largely unknown. Pre-clinical and clinical research indicate that ovarian hormones may play a major role.

Objective and rationale

We systematically reviewed the clinical and pre-clinical literature on the effects of ovarian hormones on the physiology of adipose tissue (AT) and the regulation of AT mass by energy intake and EE.

Search methods

Articles in English indexed in PubMed through January 2016 were searched using keywords related to: (i) reproductive hormones, (ii)

SUBMITTER: Leeners B 

PROVIDER: S-EPMC5850121 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature