Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992-2013.

ABSTRACT:

Objective

To determine recent trends in the rate and management of new cases of OA presenting to primary healthcare using UK nationally representative data.

Methods

Using the Clinical Practice Research Datalink we identified new cases of diagnosed OA and clinical OA (including OA-relevant peripheral joint pain in those aged over 45 years) using established code lists. For both definitions we estimated annual incidence density using exact person-time, and undertook descriptive analysis and age-period-cohort modelling. Demographic characteristics and management were described for incident cases in each calendar year. Sensitivity analyses explored the robustness of the findings to key assumptions.

Results

Between 1992 and 2013 the annual age-sex standardized incidence ra

SUBMITTER: Yu D 

PROVIDER: S-EPMC5850125 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature