Effect and Safety of Morphine Use in Acute Anterior ST-Segment Elevation Myocardial Infarction.

ABSTRACT:

Background

Morphine is commonly used to treat chest pain during myocardial infarction, but its effect on cardiovascular outcome has never been directly evaluated. The aim of this study was to examine the effect and safety of morphine in patients with acute anterior ST-segment elevation myocardial infarction followed up for 1 year.

Methods and results

We used the database of the CIRCUS (Does Cyclosporine Improve Outcome in ST Elevation Myocardial Infarction Patients) trial, which included 969 patients with anterior ST-segment elevation myocardial infarction, admitted for primary percutaneous coronary intervention. Two groups were defined according to use of morphine preceding coronary angiography. The composite primary outcome was the combined incidence of major adverse cardi

SUBMITTER: Bonin M 

PROVIDER: S-EPMC5850179 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature