HIV Infection, Immunosuppression, and Age at Diagnosis of Non-AIDS-Defining Cancers.

ABSTRACT:

Background

It is unclear whether immunosuppression leads to younger ages at cancer diagnosis among people living with human immunodeficiency virus (PLWH). A previous study found that most cancers are not diagnosed at a younger age in people with AIDS, with the exception of anal and lung cancers. This study extends prior work to include all PLWH and examines associations between AIDS, CD4 count, and age at cancer diagnosis.

Methods

We compared the median age at cancer diagnosis between PLWH in the North American AIDS Cohort Collaboration on Research and Design and the general population using data from the Surveillance, Epidemiology and End Results Program. We used statistical weights to adjust for population differences. We also compared median age at cancer diagnosis by AID

SUBMITTER: Shiels MS 

PROVIDER: S-EPMC5850313 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature