The Impact of a Reported Penicillin Allergy on Surgical Site Infection Risk.

ABSTRACT:

Background

A reported penicillin allergy may compromise receipt of recommended antibiotic prophylaxis intended to prevent surgical site infections (SSIs). Most patients with a reported penicillin allergy are not allergic. We determined the impact of a reported penicillin allergy on the development of SSIs.

Methods

In this retrospective cohort study of Massachusetts General Hospital hip arthroplasty, knee arthroplasty, hysterectomy, colon surgery, and coronary artery bypass grafting patients from 2010 to 2014, we compared patients with and without a reported penicillin allergy. The primary outcome was an SSI, as defined by the Centers for Disease Control and Prevention's National Healthcare Safety Network. The secondary outcome was perioperative antibiotic use.

Results

SUBMITTER: Blumenthal KG 

PROVIDER: S-EPMC5850334 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature