Evaluating the design and reporting of pragmatic trials in osteoarthritis research.

ABSTRACT:

Objectives

Among the challenges in health research is translating interventions from controlled experimental settings to clinical and community settings where chronic disease is managed daily. Pragmatic trials offer a method for testing interventions in real-world settings but are seldom used in OA research. The aim of this study was to evaluate the literature on pragmatic trials in OA research up to August 2016 in order to identify strengths and weaknesses in the design and reporting of these trials.

Methods

We used established guidelines to assess the degree to which 61 OA studies complied with pragmatic trial design and reporting. We assessed design according to the pragmatic-explanatory continuum indicator summary and reporting according to the pragmatic trials extension

SUBMITTER: Ali SA 

PROVIDER: S-EPMC5850497 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature