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Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus.


ABSTRACT: A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian adaptation mutation PB2 Q591K.

SUBMITTER: Mak GCK 

PROVIDER: S-EPMC5850530 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus.

Mak Gannon Chun Kit GCK   Kwan Mike Yat-Wah MY   Mok Chris Ka Pun CKP   Lo Janice Yee Chi JYC   Peiris Malik M   Leung Chi Wai CW  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20180101 1


A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian adaptation mutation PB2 Q591K. ...[more]

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