Serum omega-3 fatty acids and treatment outcomes among women undergoing assisted reproduction.

ABSTRACT:

Study question

Are serum polyunsaturated fatty acids (PUFA) concentrations, including omega-3 (ω3-PUFA) and omega-6 (ω6-PUFA), related to ART outcomes?

Summary answer

Serum levels of long-chain ω3-PUFA were positively associated with probability of live birth among women undergoing ART.

What is known already

Intake of ω3-PUFA improves oocyte and embryo quality in animal and human studies. However, a recent cohort study found no relation between circulating ω3-PUFA levels and pregnancy rates after ART.

Study design size, and duration

This analysis included a random sample of 100 women from a prospective cohort study (EARTH) at the Massachusetts General Hospital Fertility Center who underwent 136 ART cycles within one year of blood collection.

Participants/mat

SUBMITTER: Chiu YH 

PROVIDER: S-EPMC5850735 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature