Ontology highlight
ABSTRACT:
SUBMITTER: Ramaswamy S
PROVIDER: S-EPMC5850871 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature

Human reproduction (Oxford, England) 20171001 10
<h4>Study question</h4>What is the genetic landscape within the testis of the juvenile rhesus monkey (Macaca mulatta) that underlies the decision of undifferentiated spermatogonia to commit to a pathway of differentiation when puberty is induced prematurely by exogenous LH and FSH stimulation?<h4>Summary answer</h4>Forty-eight hours of gonadotrophin stimulation of the juvenile monkey testis resulted in the appearance of differentiating B spermatogonia and the emergence of 1362 up-regulated and 2 ...[more]