In Vitro Bioactivity of Methanolic Extracts from Amphipterygium adstringens (Schltdl.) Schiede ex Standl., Chenopodium ambrosioides L., Cirsium mexicanum DC., Eryngium carlinae F. Delaroche, and Pithecellobium dulce (Roxb.) Benth. Used in Traditional Medicine in Mexico.

ABSTRACT: Seven out of eight methanolic extracts from five plants native to Mexico were inactive against ten bacterial strains of clinical interest. The fruit extract of Chenopodium ambrosioides inhibited the bacteria Enterococcus faecalis (MIC = 4375 μg/ml), Escherichia coli (MIC = 1094 μg/ml), and Salmonella typhimurium (MIC = 137 μg/ml). The fruit extract of C. ambrosioides was with CC₅₀ = 45 μg/ml most cytotoxic against the cell-line Caco-2, followed by the leaf extract from Pithecellobium dulce (CC₅₀ = 126 μg/ml); interestingly, leaves of C. ambrosioides (CC₅₀ = 563 μg/ml) and bark of P. dulce (CC₅₀ = 347 μg/ml) extracts were much less cytotoxic. W

SUBMITTER: Knauth P 

PROVIDER: S-EPMC5851410 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature