Salivary microbial profiles in relation to age, periodontal, and systemic diseases.

ABSTRACT:

Background

Analysis of saliva is emerging as a promising tool to diagnose and monitor diseases which makes determination of the salivary microbial profile in different scenarios essential.

Objective

To evaluate the effects of age, periodontal disease, sex, smoking, and medical conditions on the salivary microbial profile.

Design

A randomly selected sample of 441 individuals was enrolled (51% women; mean age 48.5±16.8). Participants answered a health questionnaire and underwent an oral examination. Stimulated saliva was collected and the counts of 41 bacteria were determined by checkerboard DNA-DNA hybridization.

Results

Elderly participants (> 64 years old) presented a significant increase in 24 out of 41 bacterial species compared to adults (≤ 64 years old). E

SUBMITTER: Lira-Junior R 

PROVIDER: S-EPMC5851536 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature