Risk Stratification Using Oxygenation in the First 24 Hours of Pediatric Acute Respiratory Distress Syndrome.

ABSTRACT:

Objective

Oxygenation measured 24 hours after acute respiratory distress syndrome onset more accurately stratifies risk, relative to oxygenation at onset, in both children and adults. However, waiting 24 hours is problematic, especially for interventions that are more efficacious early in the disease course. We aimed to delineate whether oxygenation measured at timepoints earlier than 24 hours would retain predictive validity in pediatric acute respiratory distress syndrome.

Design

Observational cohort study.

Setting

Two large, academic PICUs.

Patients

Invasively ventilated children with acute respiratory distress syndrome.

Interventions

None.

Measurements and main results

PaO2/FIO2 and oxygenation index (mean airway pressure × FIO2 × 100)/PaO2) w

SUBMITTER: Yehya N 

PROVIDER: S-EPMC5851808 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature