Ontology highlight
ABSTRACT:
SUBMITTER: Pastorino R
PROVIDER: S-EPMC5852094 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Pastorino Roberta R Puggina Anna A Carreras-Torres Robert R Lagiou Pagona P Holcátová Ivana I Richiardi Lorenzo L Kjaerheim Kristina K Agudo Antonio A Castellsagué Xavier X Macfarlane Tatiana V TV Barzan Luigi L Canova Cristina C Thakker Nalin S NS Conway David I DI Znaor Ariana A Healy Claire M CM Ahrens Wolfgang W Zaridze David D Szeszenia-Dabrowska Neonilia N Lissowska Jolanta J Fabianova Eleonora E Mates Ioan Nicolae IN Bencko Vladimir V Foretova Lenka L Janout Vladimir V Brennan Paul P Gaborieau Valérie V McKay James D JD Boccia Stefania S
Scientific reports 20180314 1
With the aim to dissect the effect of adult height on head and neck cancer (HNC), we use the Mendelian randomization (MR) approach to test the association between genetic instruments for height and the risk of HNC. 599 single nucleotide polymorphisms (SNPs) were identified as genetic instruments for height, accounting for 16% of the phenotypic variation. Genetic data concerning HNC cases and controls were obtained from a genome-wide association study. Summary statistics for genetic association w ...[more]