Mortality risk after cancer diagnosis in kidney transplant recipients: the limitations of analyzing hospital administration data alone.

ABSTRACT: Administrative data are frequently used for epidemiological studies but its usefulness to analyze cancer epidemiology after kidney transplantation is unclear. In this retrospective population-based cohort study, we identified every adult kidney-alone transplant performed in England (2003-2014) using administrative data from Hospital Episode Statistics. Results were compared to the hospitalized adult general population in England to calculate standardized incidence and mortality ratios. Data were analyzed for 19,883 kidney allograft recipients, with median follow-up 6.0 years' post-transplantation. Cancer incidence was more common after kidney transplantation compared to the general population in line with published literature (standardized incidence ratio 2.47, 95% CI: 2.34-2.61). In a Cox

SUBMITTER: Jackson-Spence F 

PROVIDER: S-EPMC5852366 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature