The seasonal influence of climate and environment on yellow fever transmission across Africa.

ABSTRACT:

Background

Yellow fever virus (YFV) is a vector-borne flavivirus endemic to Africa and Latin America. Ninety per cent of the global burden occurs in Africa where it is primarily transmitted by Aedes spp, with Aedes aegypti the main vector for urban yellow fever (YF). Mosquito life cycle and viral replication in the mosquito are heavily dependent on climate, particularly temperature and rainfall. We aimed to assess whether seasonal variations in climatic factors are associated with the seasonality of YF reports.

Methodology/principal findings

We constructed a temperature suitability index for YFV transmission, capturing the temperature dependence of mosquito behaviour and viral replication within the mosquito. We then fitted a series of multilevel logistic regression models t

SUBMITTER: Hamlet A 

PROVIDER: S-EPMC5854243 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature