Engineering antimicrobial coating of archaeal poly-γ-glutamate-based materials using non-covalent crosslinkages.

ABSTRACT: We are now entering a new age of intelligent material development using fine, sustainable polymers from extremophiles. Herein we present an innovative (but simple) means of transforming archaeal poly-γ-glutamate (PGA) into extremely durable polyionic complexes with potent antimicrobial performance. This new supra-polymer material (called PGA/DEQ) was subjected to nuclear magnetic resonance and X-ray diffraction spectroscopies to characterize in structural chemistry. Calorimetric measurements revealed its peculiar thermal properties; to the best of our knowledge, it is one of the most heat-resistant biopolymer-based polyionic complexes developed to date. PGA/DEQ is particularly useful in applications where surface functionalization is important, e.g., antimicrobial coatings. The spontaneous

SUBMITTER: Ashiuchi M 

PROVIDER: S-EPMC5854621 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature