Cushing's sign and severe traumatic brain injury in children after blunt trauma: a nationwide retrospective cohort study in Japan.

ABSTRACT: OBJECTIVE:We tested whether Cushing's sign could predict severe traumatic brain injury (TBI) requiring immediate neurosurgical intervention (BI-NSI) in children after blunt trauma. DESIGN:Retrospective cohort study using Japan Trauma Data Bank. SETTING:Emergency and critical care centres in secondary and tertiary hospitals in Japan. PARTICIPANTS:Children between the ages of 2 and 15 years with Glasgow Coma Scale motor scores of 5 or less at presentation after blunt trauma from 2004 to 2015 were included. A total of 1480 paediatric patients were analysed. PRIMARY OUTCOME MEASURES:Patients requiring neurosurgical intervention within 24 hours of hospital arrival and patients who died due to isolated severe TBI were defined as BI-NSI. The combination of systolic blood pressure (SBP) and heart

SUBMITTER: Yumoto T 

PROVIDER: S-EPMC5855168 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature