Heritability of glaucoma and glaucoma-related endophenotypes: systematic review and meta-analysis protocol.

ABSTRACT: INTRODUCTION:Glaucoma is the second leading cause of age-related vision loss worldwide; it is an umbrella term that is used to describe a set of complex ocular disorders with a multifactorial aetiology. Both genetic and lifestyle risk factors for glaucoma are well established. Thus far, however, systematic reviews on the heritability of glaucoma have focused on the heritability of primary open-angle glaucoma only. No systematic review has comprehensively reviewed or meta-analysed the heritability of other types of glaucoma, including glaucoma-related endophenotypes. The aim of this study will be to identify relevant scientific literature regarding the heritability of both glaucoma and related endophenotypes and summarise the evidence by performing a systematic review and meta-analysis. MET

SUBMITTER: Asefa NG 

PROVIDER: S-EPMC5855254 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature