Dopaminergic Genetic Variants and Voluntary Externally Paced Exercise Behavior.

ABSTRACT:

Purpose

Most candidate gene studies on the neurobiology of voluntary exercise behavior have focused on the dopaminergic signaling pathway and its role in the mesolimbic reward system. We hypothesized that dopaminergic candidate genes may influence exercise behavior through additional effects on executive functioning and that these effects are only detected when the types of exercise activity are taken into account.

Methods

Data on voluntary exercise behavior and at least one single-nucleotide polymorphism/variable number of tandem repeat (VNTR) were available for 12,929 participants of the Netherlands Twin Registry. Exercise activity was classified as externally paced if a high level of executive function skill was required. The total volume of voluntary exercise (minutes pe

SUBMITTER: VAN DER Mee DJ 

PROVIDER: S-EPMC5856580 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature