Zika virus epidemiology in Bolivia: A seroprevalence study in volunteer blood donors.

ABSTRACT:

Background

Zika virus (ZIKV), was widely reported in Latin America and has been associated with neuropathologies, as microcephaly, but only few seroprevalence studies have been published to date. Our objective was to determine the seroprevalence amongst Bolivian blood donors and estimate the future potential circulation of the virus.

Methodology

A ZIKV seroprevalence study was conducted between December 2016 and April 2017 in 814 asymptomatic Bolivian volunteer blood donors residing in various eco-environments corresponding to contrasting entomological activities. It was based on detection of IgG to ZIKV using NS1 ELISA screening, followed by a seroneutralisation test in case of positive or equivocal ELISA result.

Conclusions/significance

Analysis revealed that ZIKV c

SUBMITTER: Saba Villarroel PM 

PROVIDER: S-EPMC5858838 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature