Epidemiological features of chronic hepatitis C infection caused by remunerated blood donors: A nearly 27-year period survey.

ABSTRACT:

Aim

To understand the prevalence of hepatitis C virus (HCV) infection in blood donors over a nearly 27-year interval and to explore the factors that affect the outcome of HCV infection.

Methods

A retrospective and cross-sectional study was conducted. The participants, mostly plasma donors, were selected from three administrative villages in the Jiangsu province in Eastern China. A questionnaire was administered among the villagers who had a history of blood donation from the late 1980s to the early 1990s. All participants underwent physical examination, liver B-ultrasonography, and liver stiffness measurement. In addition, 10 mL of blood was collected from each participant to measure simple liver function parameters (albumin, alanine aminotransferase, aspirate aminotransfera

SUBMITTER: Tan YW 

PROVIDER: S-EPMC5859227 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature