Daily Physical Activity Patterns During the Early Stage of Alzheimer's Disease.

ABSTRACT:

Background

Alzheimer's disease (AD) is a neurodegenerative disease that results in severe disability. Very few studies have explored changes in daily physical activity patterns during early stages of AD when components of physical function and mobility may be preserved.

Objective

Our study explored differences in daily physical activity profiles, independent of the effects of non-cognitive factors including physical function and age, among individuals with mild AD compared to controls.

Methods

Patients with mild AD and controls (n = 92) recruited from the University of Kansas Alzheimer's Disease Center Registry, wore the Actigraph GT3X+ for seven days, and provided objective physical function (VO2 max) and mobility data. Using multivariate linear regression, we explor

SUBMITTER: Varma VR 

PROVIDER: S-EPMC5859579 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature