PathwayMapper: a collaborative visual web editor for cancer pathways and genomic data.

ABSTRACT:

Motivation

While existing network visualization tools enable the exploration of cancer genomics data, most biologists prefer simplified, curated pathway diagrams, such as those featured in many manuscripts from The Cancer Genome Atlas (TCGA). These pathway diagrams typically summarize how a pathway is altered in individual cancer types, including alteration frequencies for each gene.

Results

To address this need, we developed the web-based tool PathwayMapper, which runs in most common web browsers. It can be used for viewing pre-curated cancer pathways, or as a graphical editor for creating new pathways, with the ability to overlay genomic alteration data from cBioPortal. In addition, a collaborative mode is available that allows scientists to co-operate interactively on con

SUBMITTER: Bahceci I 

PROVIDER: S-EPMC5859976 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature