Annotatr: genomic regions in context.

ABSTRACT:

Motivation

Analysis of next-generation sequencing data often results in a list of genomic regions. These may include differentially methylated CpGs/regions, transcription factor binding sites, interacting chromatin regions, or GWAS-associated SNPs, among others. A common analysis step is to annotate such genomic regions to genomic annotations (promoters, exons, enhancers, etc.). Existing tools are limited by a lack of annotation sources and flexible options, the time it takes to annotate regions, an artificial one-to-one region-to-annotation mapping, a lack of visualization options to easily summarize data, or some combination thereof.

Results

We developed the annotatr Bioconductor package to flexibly and quickly summarize and plot annotations of genomic regions. The annotat

SUBMITTER: Cavalcante RG 

PROVIDER: S-EPMC5860117 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature