VICTOR: genome-based phylogeny and classification of prokaryotic viruses.

ABSTRACT:

Motivation

Bacterial and archaeal viruses are crucial for global biogeochemical cycles and might well be game-changing therapeutic agents in the fight against multi-resistant pathogens. Nevertheless, it is still unclear how to best use genome sequence data for a fast, universal and accurate taxonomic classification of such viruses.

Results

We here present a novel in silico framework for phylogeny and classification of prokaryotic viruses, in line with the principles of phylogenetic systematics, and using a large reference dataset of officially classified viruses. The resulting trees revealed a high agreement with the classification. Except for low resolution at the family level, the majority of taxa was well supported as monophyletic. Clusters obtained with distance threshol

SUBMITTER: Meier-Kolthoff JP 

PROVIDER: S-EPMC5860169 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature