Subjective cognitive concerns are associated with objective memory performance in Caucasian but not African-American persons.

ABSTRACT:

Objective

subjective cognitive concerns (SCC) have been proposed as a means of identifying individuals at risk for Alzheimer's disease (AD). However, the utility of SCCs has not been well-explored for African-Americans, who are twice as likely to develop AD dementia as Caucasians. We investigated whether race affects the association between SCCs and objective memory performance.

Methods

we used a composite of three SCC questionnaires, and three challenging episodic memory tests. We studied 289 (61% female; African-American n = 47) clinically normal older individuals. Two hierarchical linear regressions assessed the modifying role of race on the association between SCC and objective memory performance. The first regression was conducted on the full sample, while the second ma

SUBMITTER: Jackson JD 

PROVIDER: S-EPMC5860175 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature