LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering.

ABSTRACT:

Summary

To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay.

Availability and implementation

R package LEAP available on CRAN.

Contact

[e-mail].

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Specht AT 

PROVIDER: S-EPMC5860270 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature