EMHP: an accurate automated hole masking algorithm for single-particle cryo-EM image processing.

ABSTRACT:

Summary

The Electron Microscopy Hole Punch (EMHP) is a streamlined suite of tools for quick assessment, sorting and hole masking of electron micrographs. With recent advances in single-particle electron cryo-microscopy (cryo-EM) data processing allowing for the rapid determination of protein structures using a smaller computational footprint, we saw the need for a fast and simple tool for data pre-processing that could run independent of existing high-performance computing (HPC) infrastructures. EMHP provides a data preprocessing platform in a small package that requires minimal python dependencies to function.

Availability and implementation

https://www.bitbucket.org/chazbot/emhp Apache 2.0 License.

Contact

[e-mail].

Supplementary information

Supplem

SUBMITTER: Berndsen Z 

PROVIDER: S-EPMC5860320 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature