Associations of Leukocyte Telomere Length With Aerobic and Muscular Fitness in Young Adults.

ABSTRACT: Decline in both telomere length and physical fitness over the life course may contribute to increased risk of several chronic diseases. The relationship between telomere length and aerobic and muscular fitness is not well characterized. We examined whether there are cross-sectional associations of mean relative leukocyte telomere length (LTL) with objective measures of aerobic fitness, muscle strength, and muscle endurance, using data on 31-year-old participants of the Northern Finland Birth Cohort 1966 (n = 4,952-5,205, varying by exposure-outcome analysis). Aerobic fitness was assessed by means of heart rate measurement following a standardized submaximal step test; muscular fitness was assessed by means of a maximal isometric handgrip strength test and a test of lower-back trunk muscle

SUBMITTER: Williams DM 

PROVIDER: S-EPMC5860435 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature