Identifying Clinically Significant Irritability in Early Childhood.

ABSTRACT: OBJECTIVE:Advances in developmentally sensitive measurement have enabled differentiation of normative versus clinically salient irritability in early childhood. However, clinical application of these measures is still nascent. The authors developed an optimized model of clinically salient irritable behaviors at preschool age. Based on this model, the authors derived an empirically based cutoff in relation to concurrent DSM-5 irritability-related disorders (i.e., oppositional defiant disorder, disruptive mood dysregulation disorder, other depressive disorders) and used longitudinal models to test the predictive validity of the cutoff for impairment and irritability trajectories and later DSM disorders. METHOD:Preschool children oversampled for irritability were followed over 3 time points i

SUBMITTER: Wiggins JL 

PROVIDER: S-EPMC5860673 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature