Soluble transferrin receptor levels are positively associated with insulin resistance but not with the metabolic syndrome or its individual components.

ABSTRACT: The metabolic syndrome (MetS) is known to be associated with elevated serum ferritin levels. The possible association with other Fe markers has been less well studied. We aimed to investigate the cross-sectional association of soluble transferrin receptor (sTfR) and ferritin levels with the MetS components, insulin resistance and glycosylated Hb (HbA1C). The sample consisted of 725 adults, aged 19-93 years (284 men, 151 premenopausal and 290 postmenopausal women), from the Croatian island of Vis. Serum sTfR and ferritin levels were measured by immunoturbidimetry and electrochemiluminescence assays, respectively. The MetS was defined using modified international consensus criteria. Logistic and linear regression analyses were conducted to investigate the associations adjusting for age, fibr

SUBMITTER: Suarez-Ortegon MF 

PROVIDER: S-EPMC5860738 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature