Molecular strain typing of Trichophyton mentagrophytes (T. mentagrophytes var. interdigitale) using non-transcribed spacer region as a molecular marker.

ABSTRACT:

Background & objectives

: Dermatophytes are keratinophilic fungi that infect keratinized tissues of human and animal origin. Trichophyton mentagrophytes is considered to be a species complex composed of several strains, which include both anthropophiles and zoophiles. Accurate discrimination is critical for comprehensive understanding of the clinical and epidemiological implications of the genetic heterogeneity of this complex. Molecular strain typing renders an effective way to discriminate each strain. The objective of the study was to characterize T. mentagrophytes clinical isolates to sub-species level using molecular techniques and non-transcribed spacer (NTS) region as marker.

Methods

Sixty four T. mentagrophytes clinical isolates were identified by phenotypic methods.

SUBMITTER: Ramaraj V 

PROVIDER: S-EPMC5861475 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature