Intravitreal rituximab for the treatment of a secondary intraocular relapse of a large B-cell lymphoma.

ABSTRACT:

Purpose

To report a rare case of secondary intraocular lymphoma treated with intravitreal rituximab, following pars plana vitrectomy.

Observations

A 74-year-old female with history of parotid gland large B-cell lymphoma presented bilateral intraocular recurrence 10 years after the onset of the primary malignancy. Systemic work-up including PET/CT Scan, bone marrow biopsy, brain MRI and CSF analysis were unremarkable, and the patient declined to undergo systemic chemotherapy. Vision loss in her left eye was severe due to significant sub-retinal pigment epithelium (RPE) infiltration involving the macula; this eye was treated with external beam radiation therapy. On the right eye, the relapse manifested with vitreous involvement and fovea-sparing multifocal, sub-RPE infiltratio

SUBMITTER: Echegaray JJ 

PROVIDER: S-EPMC5861753 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature