Heart failure-potential new targets for therapy.

ABSTRACT:

Introduction/background

Heart failure is a major cause of cardiovascular morbidity and mortality. This review covers current heart failure treatment guidelines, emerging therapies that are undergoing clinical trial, and potential new therapeutic targets arising from basic science advances.

Sources of data

A non-systematic search of MEDLINE was carried out. International guidelines and relevant reviews were searched for additional articles.

Areas of agreement

Angiotensin-converting enzyme inhibitors and beta-blockers are first line treatments for chronic heart failure with reduced left ventricular function.

Areas of controversy

Treatment strategies to improve mortality in heart failure with preserved left ventricular function are unclear.

Growing points

M

SUBMITTER: Nabeebaccus A 

PROVIDER: S-EPMC5862241 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature