A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks.

ABSTRACT: The genetic, proteomic, disease and pharmacological studies have generated rich data in protein interaction, disease regulation and drug activities useful for systems-level study of the biological, disease and drug therapeutic processes. These studies are facilitated by the established and the emerging computational methods. More recently, the network descriptors developed in other disciplines have become more increasingly used for studying the protein-protein, gene regulation, metabolic, disease networks. There is an inadequate coverage of these useful network features in the public web servers. We therefore introduced upto 313 literature-reported network descriptors in PROFEAT web server, for describing the topological, connectivity and complexity characteristics of undirected unweighted

SUBMITTER: Zhang P 

PROVIDER: S-EPMC5862332 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature