Brain Transcriptome Profiling Analysis of Nile Tilapia (Oreochromis niloticus) Under Long-Term Hypersaline Stress.

ABSTRACT: The fish brain plays an important role in controlling growth, development, reproduction, and adaptation to environmental change. However, few studies stem from the perspective of whole transcriptome change in a fish brain and its response to long-term hypersaline stress. This study compares the differential transcriptomic responses of juvenile Nile tilapia (Oreochromis niloticus) maintained for 8 weeks in brackish water (16 practical salinity units, psu) and in freshwater. Fish brains from each treatment were collected for RNA-seq analysis to identify potential genes and pathways responding to hypersaline stress. A total of 27,089 genes were annotated, and 391 genes were expressed differently in the salinity treatment. Ten pathways containing 40 differentially expressed genes were i

SUBMITTER: Liu Y 

PROVIDER: S-EPMC5862863 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature