MicroRNA expression profile in primary lung cancer cells lines obtained by endobronchial ultrasound transbronchial needle aspiration.

ABSTRACT:

Background

Novel cancer biomarkers like microRNA (miRNA) are promising tools to gain a better understanding of lung cancer pathology and yield important information to guide therapy. In recent years, new less invasive methods for the diagnosis and staging of NSCLC have become key tools in thoracic oncology and the worldwide spread of endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA). However, appropriate specimen handling is mandatory to achieve adequate results and reproducibility. The aim of this single centre prospective study was to evaluate the feasibility of a complete miRNA expression profile in fresh NSCLC cell lines obtained by EBUS-TBNA.

Methods

Patients with proven NSCLC underwent EBUS-TBNA for the diagnosis of suspect lymph node metastasis, an

SUBMITTER: Guarize J 

PROVIDER: S-EPMC5863144 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature