The Effects of Combinations of Cognitive Impairment and Pre-frailty on Adverse Outcomes from a Prospective Community-Based Cohort Study of Older Chinese People.

ABSTRACT:

Objectives

To examine how various combinations of cognitive impairment (overall performance and specific domains) and pre-frailty predict risks of adverse outcomes; and to determine whether cognitive frailty may be defined as the combination of cognitive impairment and the presence of pre-frailty.

Design

Community-based cohort study.

Participants

Chinese men and women (n = 3,491) aged 65+ without dementia, Parkinson's disease and/or frailty at baseline.

Measurements

Frailty was characterized using the Cardiovascular Health Study criteria. Overall cognitive impairment was defined by a Cantonese Mini-Mental Status Examination (CMMSE) total score (<21/24/27, depending on participants' educational levels); delayed recall impairment by a CMMSE delayed recall

SUBMITTER: Yu R 

PROVIDER: S-EPMC5863513 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature