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Barriers for conducting clinical trials in developing countries- a systematic review.


ABSTRACT:

Background

Clinical trials for identification of efficient and effective new diagnostic and treatment modalities are needed to address disproportionately high burden of communicable (e.g., HIV/AIDS, tuberculosis, and malaria) and non-communicable diseases (e.g., diabetes) in developing countries. However, gross under-representation in global clinical trial platforms contributes to sustained health inequity in these countries. We reviewed the literature on barriers facing clinical researchers in developing countries for conducting clinical trials in their countries.

Methods

Literature indexed in PubMed, Embase, CINAHL and Web of Science, WHO Global Health Library were searched. Grey literature was also searched. Search key words included barriers, challenges, clinical trials

SUBMITTER: Alemayehu C 

PROVIDER: S-EPMC5863824 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature