Community-based mass treatment with azithromycin for the elimination of yaws in Ghana-Results of a pilot study.

ABSTRACT:

Introduction

The WHO yaws eradication strategy consists of one round of total community treatment (TCT) of single-dose azithromycin with coverage of > 90%.The efficacy of the strategy to reduce the levels on infection has been demonstrated previously in isolated island communities in the Pacific region. We aimed to determine the efficacy of a single round of TCT with azithromycin to achieve a decrease in yaws prevalence in communities that are endemic for yaws and surrounded by other yaws-endemic areas.

Methods

Surveys for yaws seroprevalence and prevalence of skin lesions were conducted among schoolchildren aged 5-15 years before and one year after the TCT intervention in the Abamkrom sub-district of Ghana. We used a cluster design with the schools as the primary sampling u

SUBMITTER: Abdulai AA 

PROVIDER: S-EPMC5863939 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature