Hemoglobin A_1c and Mortality in Older Adults With and Without Diabetes: Results From the National Health and Nutrition Examination Surveys (1988-2011).

ABSTRACT:

Objective

Hemoglobin A_1c (HbA_1c) level has been associated with increased mortality in middle-aged populations. The optimal intensity of glucose control in older adults with diabetes remains uncertain. We sought to estimate the risk of mortality by HbA_1c levels among older adults with and without diabetes.

Research design and methods

We analyzed data from adults aged ≥65 years (n = 7,333) from the Third National Health and Nutrition Examination Survey (NHANES III) (1998-1994) and Continuous NHANES (1999-2004) and their linked mortality data (through December 2011). Cox proportional hazards models were used to examine the relationship of HbA_1c with the risk of all-cause and cause-specific (cardiovascular disease [CVD], cancer

SUBMITTER: Palta P 

PROVIDER: S-EPMC5864101 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature