Serum cholesterol trajectories in the 10 years prior to lymphoma diagnosis.

ABSTRACT:

Purpose

Many studies suggest a role for cholesterol in cancer development. Serum cholesterol levels have been observed to be low in newly diagnosed lymphoma cases. The objective of these analyses was to examine the time-varying relationship of cholesterol with lymphomagenesis in the 10 years prior to diagnosis by lymphoma subtype.

Methods

Participants were selected from the combined membership of six National Cancer Institute-funded Cancer Research Network health plans from 1998 to 2008, excluding members with human immunodeficiency virus, cancer (except lymphoma), or organ transplants. Incident lymphoma cases within this population were ascertained and matched with up to five controls. Total serum cholesterol, high-density lipoprotein, and low-density lipoprotein were colle

SUBMITTER: Alford SH 

PROVIDER: S-EPMC5864123 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature