Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis.

ABSTRACT: Endospore formation in the Gram-positive bacterium Bacillus subtilis initiates in response to nutrient depletion and involves a series of morphological changes that result in the creation of a dormant spore. Early in this developmental process, the cell undergoes an asymmetric cell division that produces the larger mother cell and smaller forespore, the latter destined to become the mature spore. The mother cell septal membrane then engulfs the forespore, at which time an essential channel, the so-called feeding-tube apparatus, is thought to cross both membranes to create a direct conduit between the cells. At least nine proteins are required to form this channel including SpoIIQ under forespore control and SpoIIIAA-AH under the mother cell control. Several of these proteins share similari

SUBMITTER: Zeytuni N 

PROVIDER: S-EPMC5864543 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature