A long noncoding RNA promotes cellulase expression in Trichoderma reesei.

ABSTRACT:

Background

Due to its capability to secrete large quantities of plant biomass degrading enzymes (PBDE), Trichoderma reesei is widely applied for industrial purposes. In nature, expression of PBDE is efficiently regulated in this fungus. Several factors involved in this regulatory network have been identified. However, most of them are transcription factors. Long noncoding RNAs (lncRNAs) emerged as common players acting on epigenetic or transcriptional regulation in several eukaryotic organisms. To date, no lncRNA has been described in filamentous fungi.

Results

A lncRNA termed HAX1 was identified in T. reesei QM9414. In this study, it was characterized and evidence for its regulatory impact on cellulase expression was provided. Interestingly, different v

SUBMITTER: Till P 

PROVIDER: S-EPMC5865335 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature